219
84
2
1
97
Cat. No. | Product Name | ||
---|---|---|---|
L2191 | 抗乳腺癌化合物库 | 1939 compounds | |
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究; | |||
L3800 | NF-κB 通路分子库 | 729 compounds | |
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0081 |
Magrose Beads OH 6B
琼脂糖羟基磁珠 6B |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9315 |
2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]-
|
Others | Others |
2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- 是有效的mTOR 抑制剂,对于mTOR 和PI3Kα的IC50分别为0.176 μM 和 >30 μM。 | |||
TQ0257 |
FICZ
6-Formylindolo[3,2-b]carbazole |
Aryl Hydrocarbon Receptor | Immunology/Inflammation |
FICZ (6-Formylindolo[3,2-b]carbazole) 是芳烃受体 (AhR) 的有效芳基激动剂,Kd 值为70 pM。 | |||
T21000 |
PiB
2-(4-(二甲基氨基)苯基)苯并[D]噻唑-6-醇,Pittsburgh Compound-B,6-OH-BTA-1 |
Others | Others |
PiB (Pittsburgh Compound-B) 是分析 11C-PiB 的标准品。 11C-PiB 是一种用于阿尔茨海默病诊断的 β-淀粉样蛋白 PET 成像示踪剂。 | |||
T8917 |
PAR-2-IN-1
IUN76750,8-(叔丁基)-6-氯咪唑并[1,2-B]吡啶-2-羧酸甲酯 |
Protease-activated Receptor | GPCR/G Protein |
PAR-2-IN-1 (IUN76750) 是一种 PAR-2 信号通路抑制剂,具有抗炎和抗癌作用。 | |||
T9871 |
Dazonone
Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl- |
PDE | Metabolism |
Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) 是一种特异性的 PDE III 抑制剂。 | |||
T6746 |
6-Thio-2'-Deoxyguanosine
6-Thio-dG,β-TGdR |
Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
6-Thio-2'-Deoxyguanosine (β-TGdR) 是一种核苷类似物和端粒酶底物,可以通过端粒酶掺入重新合成的端粒中。 | |||
T8430 |
Senexin B
4-[[2-[6-[(4-甲基-1-哌嗪基)羰基]-2-萘基]乙基]氨基]-6-喹唑啉甲腈 |
CDK | Cell Cycle/Checkpoint |
Senexin B 是一种有效的选择性 CDK8/19 抑制剂(CDK8 和 CDK19,Kd 分别为 140 nM 和 80 nM)。 | |||
T60053 |
Hamaline
9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole |
COX | Immunology/Inflammation; Neuroscience |
Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) 是一种底物选择性环氧合酶 2 (COX-2) 抑制剂。 | |||
T37811 |
6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt)
|
Others | Others |
6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) 是 β-glucuronidase 的显色底物。 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) 可用于组织化学分析 β-glucuronidase 活性。 | |||
T37348 |
6-Chloro-7-deazapurine-β-D-riboside
|
Antifungal | Microbiology/Virology |
6-Chloro-7-deazapurine-β-D-riboside 是核苷的衍生物,显示出抗真菌活性。 | |||
T9017 |
HPK1-IN-2
Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2 |
Others; FLT; Src | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) 是一种有效且具有口服活性的造血祖细胞激酶-1 抑制剂(HPK1;IC50<0.05 µM)。它还抑制 Lck (0.05 µM<IC50<0.5 µM) 和 Flt3 (IC50<0.05 µM) 激酶活性,具有抗肿瘤活性。 | |||
T19206 |
β-Lactamase-IN-1
4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1 |
Antibacterial | Microbiology/Virology |
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) 是一种 β-Lactamase 抑制剂,针对淋病奈瑟菌的感染。 | |||
T9999 |
Sirtuin modulator 2
N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide |
Others; Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair; Others |
Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) 具有抗糖尿病、抗炎和抗肿瘤活性。 | |||
T16922 |
SPOP-IN-6b
2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide |
Others | Others |
SPOP-IN-6b 是一种有效的斑点型 POZ 蛋白 (SPOP) 抑制剂,IC50 为 3.58 μM,可用于肾癌治疗的研究。 | |||
TP1162 |
Fibrinopeptide B, human TFA (36204-23-6 free base)
FPB,human TFA,Fibrinopeptide B, human TFA |
||
FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment. | |||
TP1866L |
β-amyloid 1-11 acetate(190436-05-6 free base)
|
Beta Amyloid | Neuroscience |
β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段,可用于神经系统疾病的研究。 | |||
T9821 |
ART-CHEM-BB B025267
2-(4-二乙基氨基苯基)-6-甲基-5-苯并三唑胺 |
Others | Others |
ART-CHEM-BB B025267 是 utrophin 生成的上调剂,EC50 为 1.8 μM,可用于治疗 Duchenne 肌营养不良症的研究。 | |||
T8749 |
CS-B1628
2-(6-溴-5-甲基-2,4-二氧代-1,4-二氢噻吩并[2,3-D]嘧啶-3(2H) - 基)-,tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate,ACN-053859 |
Others | Others |
CS-B1628 (tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate) 可用于合成嘧啶衍生物,具有成为各种有机化合物(包括药物和农用化学品)起始材料的潜在用途。 | |||
T8705 |
BOT-64
|
IκB/IKK | NF-κB |
BOT-64 是一种 IKK-2 抑制剂,靶向激酶激活环结构域中的 Ser177 和/或 Ser181 残基。BOT-64 是一种可渗透细胞的苯并恶硫醇化合物。 | |||
T12574 |
PTC299
Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate |
VEGFR; Dehydrogenase | Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors |
PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) 是一种口服活性的 VEGFA mRNA 翻译抑制剂,可选择性地抑制转录后水平的 VEGF 蛋白合成。它还是二氢乳酸脱氢酶 (DHODH) 的有效抑制剂,可研究血液系统恶性肿瘤。 | |||
T6303L |
CCT128930 hydrochloride
CCT128930 hydrochloride(885499-61-6 Free base) |
Apoptosis; Akt; PKA; mTOR; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
CCT128930 hydrochloride (CCT128930 hydrochloride) 是一种选择性 AKT 抑制剂,具有抗肿瘤活性。它通过靶向 AKT 的 Met282 (PKA-AKT 嵌合体的 Met173),对 PKA 激酶具有 28 倍的选择性,对 p70S6K 具有 20 倍的选择性。 | |||
T15249 |
Estrogen receptor modulator 1
|
Estrogen Receptor/ERR | Endocrinology/Hormones |
Estrogen receptor modulator 1 是一种有效的、具有口服活性的、选择性雌激素受体(estrogen receptor)调节剂 (SERM),其 pIC50为 0.46。它能够诱导 Tamoxifen 耐药、激素非依赖性异种移植瘤的消退。 | |||
T2036 |
6-OAU
GTPL5846 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
6-OAU (GTPL5846) 是 GPR84 的替代激动剂,在 Gqi5 嵌合体存在的情况下,在 HEK293 细胞中激活人 GPR84,在 PI 测定中 EC50 为 105 nM。 | |||
T64271 | MAO-B-IN-6 | ||
MAO-B-IN-6 是一种选择性的、有效的、口服具有活力的 MAO-B 抑制剂 (IC50: 0.019 μM)。MAO-B-IN-6 在体内外的效果均优于 Safinamide。MAO-B-IN-6 具有潜力进行帕金森病 (PD) 的研究。 | |||
T63855 |
B-Raf IN 6
|
||
B-Raf IN 6 是蛋白激酶 B-Raf 的有效抑制剂 (IC50: 1.7 nM)。B-Raf IN 6 不结合二级靶点 PXR,并可抵抗快速代谢。B-Raf IN 6 对癌症疾病表现出研究潜力。 | |||
T7167 |
Purvalanol B
NG 95,(2R)-2-[[6-[(3-氯-4-羧基苯基)氨基]-9-(1-甲基乙基)-9H-嘌呤-2-基]氨基]-3-甲基-1-丁醇 |
CDK; Parasite | Cell Cycle/Checkpoint; Microbiology/Virology |
Purvalanol B (NG 95) 是选择性可逆的 ATP 竞争性 CDK 抑制剂。它在一系列其他蛋白激酶 (IC50>1000 nM) 中显示出对 CDK 的选择性。它抑制耐氯喹菌株 P. falciparum 的生长。 | |||
T79893 |
Cbl-b-IN-6
|
E1/E2/E3 Enzyme | Ubiquitination |
Cbl-b-IN-6 (Compound 246),作为casitas B系淋巴瘤(Cbl-b)和c-Cbl的抑制剂,其IC50值分别为5.8 nM和4.4 nM。 | |||
T39865 |
β-Lactamase-IN-6
|
||
β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity. | |||
T2274 |
SC79
SC 79,2-氨基-6-氯-alpha-氰基-3-(乙氧羰基)-4H-1-苯并吡喃-4-乙酸乙酯 |
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
SC79 是一个 AKT 激动剂,具有特异性和血脑屏障渗透性。SC79 可以特异性结合 AKT 的 PH 结构域,激活胞质中 AKT,并抑制 AKT 膜转位。SC79 具有神经保护活性。 | |||
T5096 |
SRT 1720
N-[2-[3-(1-哌嗪基甲基)咪唑并[2,1-B]噻唑-6-基]苯基]-2-喹喔啉甲酰胺 |
Sirtuin; Autophagy | Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair |
SRT 1720 是人 SIRT1 的选择性激活剂 ,EC1.5为 0.16 μM,对 SIRT2 和 SIRT3 的效力要低 230 倍以上。 | |||
T10187 |
6-Raloxifene-β-D-glucopyranoside
|
Others | Others |
6-Raloxifene-β-D-glucopyranoside is a benzothiophene glucuronidated at the 6' position. It is a selective and orally active estrogen receptor antagonist. 6-Raloxifene-β-D-glucopyranoside can be used for inhibiting bone loss, resorption, and lowering lipid | |||
T8346 |
SRT 1460
3,4,5-三甲氧基-N-(2-(3-(哌嗪-1-基甲基)咪唑并[2,1-B]噻唑-6-基)苯基)苯甲酰胺,SRT1460 |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
SRT 1460 是一种有效的SIRT1激动剂,其EC1.5值为 2.9 μM。 | |||
T18877 |
β-Estradiol-6-one 6-(O-carboxymethyloxime)
|
Others | Others |
β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker utilized for PROTAC synthesis[1]. | |||
T10555 |
BJE6-106
B106 |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM). BJE6-106 induces caspase-dependent apoptosis with tumor-specific effect. | |||
T10655 |
c-Met inhibitor 1
3-[(2-甲基-2H-吲唑-5-基)硫基]-6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-B]哒嗪 |
c-Met/HGFR | Tyrosine Kinase/Adaptors |
c-Met inhibitor 1 是一种 c-Met 受体信号通路抑制剂,可用于癌症的治疗,包括胶质母细胞瘤、胃癌和胰腺癌。 | |||
T19159 |
Mal-β-CD
6-O-alpha-D-Maltosyl-beta-cyclodextrin |
Others | Others |
Mal-β-CD is a cellular cholesterol modifier. It can form a soluble inclusion complex with cholesterol. | |||
T37812 |
6-O-Sulfo-β-cyclodextrin (sodium salt)
|
||
6-O-Sulfo-β-cyclodextrin is a sulfated cyclodextrin.1It has been used for the chiral separation of nadolol racemates by capillary electrophoresis. 1.Wang, F., Dowling, T., Bicker, G., et al.Electrophoretic chiral separation of pharmaceutical compounds with multiple stereogenic centers in charged cyclodextrin mediaJ. Sep. Sci.24(5)378-384(2001) | |||
T18876 |
β-Estradiol-6-CMO-PEG3-biotin
|
Others | Others |
β-Estradiol-6-CMO-PEG3-biotin serves as a cleavable 3-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T6435 |
CCT129202
2-[4-[6-氯-2-(4-二甲基氨基苯基)-3H-咪唑并[4,5-B]吡啶-7-基]哌嗪-1-基]-N-(噻唑-2-基)乙酰胺 |
Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic |
CCT129202 是一种 ATP 竞争性泛极光激酶抑制剂,作用于 Aurora A、Aurora B 和 Aurora C,IC50 分别为 0.042 μM、0.198 μM 和 0.227 μM。 | |||
T39593 |
SPOP-IN-6b hydrochloride
|
||
SPOP-IN-6b hydrochloride is a highly effective inhibitor of speckle-type POZ protein (SPOP), exhibiting an IC50 value of 3.58 μM. | |||
T33850 |
Oxytocin, deamino-6-carba-
Deamino-6-carbaoxytocin,beta-Deaminocystathionine-oxytocin |
||
Deamino-6-carba-oxytoxin (dC60), a potent oxytocin analog considered to be resistant to some of the physiologically significant enzymic systems. | |||
TNU0301 |
2’-b-C-Methyl-6-azauridine
|
||
2'-b-C-Methyl-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; 2'-Modified nucleoside. | |||
TNU0304 |
1-(b-D-Xylofuranosyl)-6-azauracil
|
||
1-(b-D-Xylofuranosyl)-6-azauracil is a Nucleoside Derivative - Xylo-nucleoside; 6-Aza-uridine. | |||
T29476 |
6-OH-BTA-0
Pittsburgh Compound-B precursor,11C-PiB Precursor |
||
6-OH-BTA-0 is the precursor for preparing 11C-PiB, which is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis. | |||
T77512 |
1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-
|
Others | Others |
1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-可能具有抗肿瘤活性。 | |||
T10181 |
6-beta-Naloxol D5 hydrochloride
6β-Naloxol D5 hydrochloride |
Others | Others |
6-beta-Naloxol D5 hydrochloride is a deuterium-labeled opioid antagonist, closely related to naloxone, that serves as an effective compound in the field of chemical research. | |||
T65599 |
6-Methoxy-1H-pyrrolo[2,3-b]pyridine
|
||
6-Methoxy-1H-pyrrolo[2,3-b]pyridine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65599,CAS号为 896722-53-5。 | |||
TP1603 |
β-Casomorphin (1-6), bovine
|
||
β-Casomorphin (1-6), bovine is a opioid-like bioactive peptide of β-Casomorphin. | |||
T2246 |
LRRK2-IN-1
5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮 |
Apoptosis; LRRK2; CDK | Apoptosis; Autophagy; Cell Cycle/Checkpoint |
LRRK2-IN-1 是一种选择性的LRRK2有效抑制剂,作用于 LRRK2 (G2019S) 和 LRRK2 (WT),IC50值分别为 6 nM 和 13 nM。 | |||
T64055 | SPOP-IN-6b dihydrochloride | ||
SPOP-IN-6b dihydrochloride 是斑型 POZ 蛋白 (SPOP) 的有效抑制剂 (IC50: 3.58 μM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3O2784 |
Vitamin B6
维生素B6 |
Others | Others |
Vitamin B6 是人体某些辅酶的成分,参与多种代谢反应,特别是与氨基酸代谢有关。维生素B6在防治妊娠和放射病呕吐中的临床应用。 | |||
T6S0735 |
Flavokawain B
黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone |
Apoptosis; Others | Apoptosis; Others |
Flavokawain B (Flavokavain B) 是从卡瓦醉椒的根提取物中,分离出的查尔酮。它是一种凋亡诱导剂,可抑制各种癌细胞株生长。它以极低的无毒浓度抑制人脑内皮细胞的迁移和血管形成,具有抗血管生成活性。 | |||
TN3183 |
6-O-Benzoylphlorigidoside B
|
Others | Others |
6-O-Benzoylphlorigidoside B是一种天然产物,属于马鞭草科紫珠属,其产品编号为 TN3183,CAS号为 1246012-24-7。6-O-Benzoylphlorigidoside B可用作对照参考。 | |||
TN5254 |
Wighteone
Erythrinin B,6-Isopentenylgenistein |
Antifungal | Microbiology/Virology |
Wighteone (Erythrinin B) 是一种从 Genista ephedroides 中提取出来的小分子化合物,具有潜在的抗真菌和抗癌活性,对 EGFR L858R/T790M 突变非小细胞肺癌具有抗肿瘤作用。。 | |||
T1255 |
Tobramycin
NSC 180514,妥布霉素,Nebramycin Factor 6,Deoxykanamycin B |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Tobramycin (NSC-180514) 是一种胃肠外给药的广谱氨基糖苷类抗生素,可研究由于敏感生物引起的中度至重度细菌感染疾病。 | |||
TN6085 |
6-Methoxyspirotryprostatin B
Spirotryprostatin G |
||
6-Methoxyspirotryprostatin B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6085,CAS号为 1031727-28-2。 | |||
T21532 |
Anisodamine
6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine |
AChR | Neuroscience |
Anisodamine (6-beta-Hydroxyhyoscyamine) 是毒蕈碱和烟碱胆碱受体的拮抗剂,对毒蕈碱受体的亲和力与东莨菪碱和阿托品相似。 Anisodamine 改善休克状态下的微循环,可用于有机磷中毒的研究。 | |||
TN3192 |
6-O-trans-Cinnamoylphlorigidoside B
|
Others | Others |
6-O-trans-Cinnamoylphlorigidoside B是一种天然产物,属于马鞭草科紫珠属,其产品编号为 TN3192,CAS号为 1246012-25-8。6-O-trans-Cinnamoylphlorigidoside B可用作对照参考。 | |||
T4S1439 |
6'-O-beta-D-Glucosylgentiopicroside
6'-O-β-D-葡萄糖基龙胆苦苷,6'-O-Glucosylgentiopicroside |
Antifungal | Microbiology/Virology |
6'-O-beta-D-Glucosylgentiopicroside (6'-O-Glucosylgentiopicroside) 是一种环烯醚萜,分离自G. straminea 根中。它能显著抑制 fMLP 诱导的超氧化物生成。 | |||
TN1520 |
Isoforskolin
Coleonol B |
IL Receptor; TNF | Apoptosis; Immunology/Inflammation |
Isoforskolin 源自毛喉鞘蕊花,可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。 | |||
TN6600 |
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside 是一种吡喃葡萄糖苷,对 HIV-2 RNase H 具有抑制作用,IC50 为 5.19 μM。 | |||
T6225 |
Adenine hydrochloride
Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
T3885 |
ROSIRIDIN
6'-O-Deacetylrosiridoside C,络塞定,(-)-Rosiridin |
Others; Monoamine Oxidase | Neuroscience; Others |
Rosiridin (6'-O-Deacetylrosiridoside C) 能够抑制 MAO A 和 MAO B,有潜在的抑郁症和老年性痴呆作用。它在 10 μM 时对 MAO B 的抑制率为 83.8% (pIC50=5.38)。 | |||
T3815 |
Isoscopoletin
异莨菪亭,7-Methoxyesculetin,6-Hydroxy-7-methoxycoumarin |
Others; HBV | Microbiology/Virology; Others |
Isoscopoletin (7-Methoxyesculetin) 是艾叶中的一种活性成分。它具有显著的细胞增殖抑制作用,对人类 CCRF-CEM 白血病细胞和耐药亚系 CEM/ADR5000 作用的 IC50值分别为 4.0 μM 和 1.6 μM。它具有抑制 HBV 复制的活性。 | |||
T0746 |
Orotic acid
乳清酸,Vitamin B13,6-Carboxyuracil |
Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体,从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放,通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大,是尿素循环异常的常规新生儿筛查中的一种测量指标。 | |||
TN1799 |
Isorubrofusarin-6-O-β-gentiobioside
Isorubrofusarin 10-gentiobioside |
BACE; AChR | Neuroscience |
Isorubrofusarin-6-O-β-gentiobioside 来源于 Cassia obtusifolia Linn 种子,对 AChE 和 BACE1 具有良好的抑制活性。 | |||
TN2165 |
Rubrofusarin gentiobioside
Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷 |
ERK; NF-κB; TGF-beta/Smad | MAPK; NF-κB; Stem Cells |
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) 一种分离自决明子的、具有清除自由基作用的化合物。 | |||
TN2679 |
2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one
|
Others | Others |
2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one is a natural product from the metabolites of Hypericum revolutum ssp. | |||
TN6774 |
Emodin 6-O-β-D-glucoside
大黄素-6-O-β-D-葡萄糖苷,Glucoemodin |
Others | Others |
Emodin 6-O-β-D-glucoside (Glucoemodin) 是一种从 Reynoutria japonica 中提取的活性化合物。它具有显著的抗炎和屏障保护活性,可用于研究动脉粥样硬化及糖尿病并发症。 | |||
TN1285 |
5,6,7,40-Tetrahydroxyisoflavone-6,7-di-o-b-D-glucopyranoside
5-6-7-40-tetrahydroxyisoflavo-ne-6-7-di-o-b-d-glucopyranoside,5,6,7,4'-tetrahydroxyisoflavone-6,7-di-O-beta-D-glucopyranoside,5,6,7,4'-四羟基异黄酮-6,7-O-二葡萄糖苷 |
Others | Others |
5,6,7,4'-tetrahydroxyisoflavone-6,7-di-O-beta-D-glucopyranoside is a natural product | |||
T13265 |
Urolithin B
尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮 |
ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK | Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling |
Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物,具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子,通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性,并抑制 JNK、ERK 和 Akt 的磷酸化,并增强 AMPK 的磷酸化。 | |||
T0973L |
Pyridoxine hydrochloride
Pyridoxine HCl,吡哆醇盐酸盐,Pyridoxol (hydrochloride),吡哆醇盐酸盐(维生素B6),Vitamin B6 (hydrochloride),Vitamin B6 |
Nrf2; Endogenous Metabolite | Immunology/Inflammation; Metabolism |
Pyridoxine hydrochloride (Vitamin B6) 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中,通过 Nrf-2/HO-1 途径发挥抗氧化作用。 | |||
TN6909 |
Polyporusterone B
猪苓酮B,(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one |
Others | Others |
Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) 是一种三萜羧酸,从Polyporus umbellatusFries 中分离得到。它对自由基诱导的红细胞裂解 (溶血) 具有抑制作用。 | |||
TN5968 |
6″-O-Acetylsaikosaponin b3
6″-O-乙酰基柴胡皂苷b3 |
||
6″-O-Acetylsaikosaponin b3 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5968,CAS号为 104109-34-4。 | |||
T83271 |
6-Aldehydoisoophiopogonone B
|
||
6-Aldehydoisoophiopogonone B (Compound 24) 是从Ophiopogon japonicus 提取的同型异黄酮化合物。 | |||
T7174 |
Urolithin A
尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮 |
Apoptosis; Reactive Oxygen Species; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; Drug Metabolite | Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB |
Urolithin A 是一种鞣花酸的肠道微生物代谢产物,可诱导自噬和凋亡,抑制细胞周期进程,抑制DNA 合成,具有抗炎、抗增殖和抗氧化的特性。 | |||
TN6287 |
Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
Anisofolin B |
||
Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6287,CAS号为 1448779-19-8。 | |||
TN5493 |
Procyanidin B5
原花青素B5,Procyanidin B-5,Epicatechin-(4β→6)-epicatechin |
||
Procyanidin B5 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5493,CAS号为 12798-57-1。 | |||
T83266 |
6-Formyl-isoophiopogonanone B
|
||
6-Formyl-isoophiopogonanone B,一种同型异黄酮,源自麦冬(Ophiopogon japonicus)。 | |||
TN5875 |
6′′-O-β-D-Apiofuranosylapterin
|
||
6′′-O-β-D-Apiofuranosylapterin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5875,CAS号为 2188162-94-7。 | |||
TN2036 |
Paeonilactone B
(+)-Paeonilactone B |
NADPH-oxidase | Immunology/Inflammation |
Paeonilactone B ((+)-Paeonilactone B) 是一种来自白芍的单萜类化合物,具有神经保护活性,抑制氧化应激,在大鼠皮质细胞在抑制 H2O2 诱导的神经毒性。 | |||
T8266 |
(R)-Citronellol
D-Citronellol,(R)-(+)-β-Citronellol,(R)-3,7-二甲基-6-辛烯醇 |
Others; Endogenous Metabolite | Metabolism; Others |
(R)-Citronellol ((R)-(+)-β-Citronellol) 是一种存在于天竺葵精油中的醇单萜。它抑制肥大细胞的脱颗粒,并且不影响咖啡因的苦味感。它能够用于装饰性化妆品,盥洗用品以及非化妆品中。 | |||
TN1319 |
6'-O-β-Apiofuranosylsweroside
6'-O-beta-D-Apiofuranosylsweroside,6'-O-BETA-D-呋喃芹糖基当药苷,金银花 |
Others | Others |
6'-O-beta-D-Apiofuranosylsweroside is a natural product from Lonicera maackii. | |||
TN1414 |
Aurantio-obtusin β-D-glucoside
橙黄决明素-6-O-葡萄糖苷,Aurantio-obtusin beta-D-glucoside |
Others | Others |
Aurantio-obtusin β-D-glucoside (Aurantio-obtusin beta-D-glucoside) 是分离自决明子的 aurantio-obtusi 的葡糖苷。 | |||
TN4537 |
Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate
|
Others | Others |
Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4537,CAS号为 96287-41-1。 | |||
TN2117 |
Pulsatilloside E
3-O-B-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 23-羟基羽扇豆20(29)-烯-28–酸- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷,Pulchinenoside E,白头翁皂苷E |
Others | Others |
Pulsatilloside E (Pulchinenoside E) 是一种从毛茛科白头翁Pulsatilla chinensis (Ranunculaceae)的根中分离出来的天然产物。 | |||
TN6312 | Solagenin 6-O-β-D-quinovopyranoside | ||
Solagenin 6-O-β-D-quinovopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6312,CAS号为 184686-03-1。 | |||
TN6318 |
Neochlorogenin 6-O-β-D-quinovopyranoside
|
||
Neochlorogenin 6-O-β-D-quinovopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6318,CAS号为 711025-86-4。 | |||
TN6240 |
Demethylagrimonolide 6-O-glucoside
Desmethylagrimonolide 6-O-β-D-glucopyranoside |
||
Demethylagrimonolide 6-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6240,CAS号为 1257408-55-1。 | |||
T40589 |
6-O-β-D-Galactopyranosyl-D-galactose
|
||
6-O-beta-D-Galactopyranosyl-D-galactose, a disaccharide, is a constituent of the polysaccharide backbone characterized by beta-(1→6) glycoside linkages, with a side chain attached to the primary chain through a beta-(1→3) bond. | |||
TN3083 |
Artoindonesianin B-1
5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol |
Others | Others |
Artoindonesianin B-1 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3083,CAS号为 936006-11-0。 | |||
TN5843 |
3-O-(6'-O-Galloyl)-β-D-glucopyranosylmaltol
|
||
3-O-(6'-O-Galloyl)-β-D-glucopyranosylmaltol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5843,CAS号为 163397-38-4。 | |||
TN5679 | Benzyl 2-hydroxy-6-(β-glucosyloxy)benzoate | ||
Benzyl 2-hydroxy-6-(β-glucosyloxy)benzoate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5679,CAS号为 403857-21-6。 | |||
T81321 |
Quercetin-3-O-b-D-galactopyranosyl-(1→6)-b-D-glucopyranoside
|
||
Quercetin-3-O-b-D-galactopyranosyl-(1→6)-b-D-glucopyranoside (化合物 1),为自白仙茅 (M. delavayi) 叶中分离的黄酮甙类化合物。 | |||
T5621 |
β-Phellandrene
beta-Phellandrene,3-异丙基-6-亚甲基-1-环己烯,p-mentha-1(7),2-diene,(±)-beta-水芹烯 |
Others | Others |
β-Phellandrene (p-mentha-1(7),2-diene) 是由加拿大香脂油分馏取得,可用作精油添加剂。 | |||
TN6522 | Quercetin 7-O-(6''-O-malonyl)-beta-D-glucoside | ||
Quercetin 7-O-(6''-O-malonyl)-beta-D-glucoside是一种天然产物,属于爵床科爵床属,其产品编号为 TN6522,CAS号为 98767-37-4。Quercetin 7-O-(6''-O-malonyl)-beta-D-glucoside可用作对照参考。 | |||
TN2461 |
Loganic acid 6′-O-β-D-glucoside
8-Epi-Loganic acid-6'-O-β-D-glucoside |
Others | Others |
Loganic acid 6′-O-β-D-glucoside (8-Epi-Loganic acid-6'-O-β-D-glucoside) 是 Cistanche deserticola 的天然产物,可抑制 LPS 诱导的 NO 和 TNF-α 的产生。 | |||
TN1311 |
5,6,7,4'-Tetrahydroxyflavonol 3-O-rutinoside
6-Hydroxykaempferol 3-beta-rutinoside,6-羟基山柰酚-3-O-芸香糖苷 |
Others | Others |
6-Hydroxykaempferol 3-beta-rutinoside is a natural product | |||
TN2124 |
Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside
Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside,槲皮素3-O-(6''-没食子酰基)-Β-D-葡萄糖苷 |
Others | Others |
Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside) 是一种天然产物,对铜绿微囊藻的生长具有很强的抑制活性。 | |||
TN2123 |
Quercetin 3-O-(6''-galloyl)-β-D-galactopyranoside
Hyperin 6''-gallate,槲皮素3-O-(6''-没食子酰基)-Β-D-半乳糖苷,Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside |
MAPK; p53 | Apoptosis; MAPK |
Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside can effectively induce apoptosis via p53, MAPKs and the mitochondrial apoptotic pathways. | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00360 |
G6B Protein, Human, Recombinant (His)
G6b,G6b-B,NG31,... |
Human | HEK293 Cells |
G6B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is O95866-1. | |||
TMPY-00126 |
G6B Protein, Human, Recombinant (hFc)
G6b-B,chromosome 6 open ... |
Human | HEK293 Cells |
G6B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.2 kDa and the accession number is O95866-1. | |||
TMPY-05275 |
CD79B Protein, Human, Recombinant (His)
B29,IGB,CD79b molecule, immunoglo... |
Human | HEK293 Cells |
CD79B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.7 kDa and the accession number is P40259-1. | |||
TMPY-01081 |
SR-BI/SCARB1 Protein, Human, Recombinant (His)
SR-BI,SRB1,HDLQTL6,CD36L... |
Human | HEK293 Cells |
SR-BI/SCARB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is A0A024RBS4. | |||
TMPY-02242 |
Serpin B6 Protein, Human, Recombinant (His)
DKFZp686I04222,PTI,SPI3,PI-6,RP1-... |
Human | Baculovirus Insect Cells |
SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is ex... | |||
TMPY-03262 |
B3GNT6 Protein, Human, Recombinant (aa 44-384, His)
BGnT-6,UDP-GlcNAc:βGal β-1,3-N-acetylgluco... |
Human | Baculovirus Insect Cells |
B3GNT6 belongs to the glycosyltransferase 31 family. B3GNT6 play s an important role in the synthesis of mucin-type O-glycans in digestive organs. It catalyzes the transfer of GlcNAc from UDP-GlcNAc to GalNAcalpha1-Ser/Thr (Tn antigen) to form the core 3 structure (GlcNAcbeta1-3GalNAcalpha1-Ser/Thr). Core 3 structure exists in O-glycan which is an important precursor in the biosynthesis of mucin-type glycoproteins. Loss of core 3 could lead to the production of secreted mucins, then bacteria wou... | |||
TMPK-00839 |
ITGB6 Protein, Human, Recombinant (His)
β6,Integrin β-6,β 6,beta... |
Human | HEK293 Cells |
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene. ITGB6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.4 kDa and the accession number is ... | |||
TMPY-02842 |
UBE2L6 Protein, Human, Recombinant (His)
UBCH8,ubiquitin-conjugating enzyme E2L |
Human | E. coli |
UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modi... | |||
TMPY-02090 |
Cystatin B Protein, Human, Recombinant (His)
PME,EPM1A,STFB,ULD,cystatin B (stefin ... |
Human | E. coli |
Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the prot... | |||
TMPK-01247 |
ITGB6 Protein, Mouse, Recombinant (His)
ITGB6,Integrin β-6,Integrin b... |
Mouse | HEK293 Cells |
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene. ITGB6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.7 kDa and the accession number is ... | |||
TMPJ-00218 |
SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated
CD352,SLAM Family Member 6,Activating NK R... |
Human | HEK293 Cells |
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Pho... | |||
TMPY-02430 |
BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)
BCL5,ZNF51,B-cell CLL/lymphoma 6,... |
Human | E. coli |
The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon... | |||
TMPH-00999 |
BCL6 Protein, Human, Recombinant (His)
BCL-5,B-cell lymphoma 5 protein,B... |
Human | E. coli |
BCL6 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-00651 |
SLAMF6 Protein, Cynomolgus, Recombinant (His)
SF2000,Ly108,KALIb,SLAMF6,NTB-A,K... |
Cynomolgus | HEK293 Cells |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. SLAMF6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-H... | |||
TMPH-01606 |
BAG6 Protein, Human, Recombinant (His & Myc)
BAG-6,Protein G3,BAG family molec... |
Human | Baculovirus Insect Cells |
BAG6 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 38.7 kDa and the accession number is P46379. | |||
TMPH-01000 |
BCL6 Protein, Human, Recombinant
ZNF51,LAZ3,ZBTB27,Zinc finger protein 51,<... |
Human | E. coli |
BCL6 Protein, Human, Recombinant is expressed in E. coli. | |||
TMPK-00222 |
SLAMF6 Protein, Human, Recombinant (His & Avi)
ANK-T-B-antigen,Ly108,KALIb,SLAMF6 |
Human | HEK293 Cells |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. SLAMF6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-... | |||
TMPK-01174 |
SLAMF6 Protein, Mouse, Recombinant (aa 31-239, His)
Ly108,ANK-T-B-antigen,NTB-A,KALI,NK-T-... |
Mouse | HEK293 Cells |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. SLAMF6 Protein, Mouse, Recombinant (aa 31-239, His) is expressed in HEK293 mammalian cells wi... | |||
TMPK-00115 |
CD79B Protein, Human, Recombinant (His & Avi)
Ig-beta,CD79B,IGB,CD79b ... |
Human | HEK293 Cells |
CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruit... | |||
TMPJ-00897 |
TPSB2 Protein, Mouse, Recombinant (His)
Tryptase-2,Mast cell protease 6,Tryptase b... |
Mouse | HEK293 Cells |
Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It plays a role in innate immunity. Tpsb2 can be detected primarily in skin during embryogenesis. Tpsb2 can not be detected at early embryonic stages but is abundantly expressed in later stages with a peak at E17.5-E18.5. Tryp... | |||
TMPK-01195 |
CCL24 Protein, Mouse, Recombinant (hFc)
Ckb-6,CK-β-6,MPIF-2,CK-b... |
Mouse | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver. CCL24 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight... | |||
TMPH-01458 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Protein U22 (His)
|
HHV-6B | E. coli |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Protein U22 (His) is expressed in in vitro E. coli expression system. | |||
TMPH-01605 |
BAG6 Protein, Human, Recombinant (E. coli, His & Myc)
BAT3,BAG6,HLA-B-associat... |
Human | E. coli |
BAG6 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.7 kDa and the accession number is P46379. | |||
TMPY-02542 |
Serpin B6b Protein, Mouse, Recombinant (His)
Spi12,NK13,ovalbumin |
Mouse | Baculovirus Insect Cells |
Serpin B6b Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44 kDa and the accession number is O08804. | |||
TMPK-01196 |
CCL24 Protein, Mouse, Recombinant (His)
MPIF2,CK-beta-6,member 24,CK-β- |
Mouse | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver. CCL24 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight... | |||
TMPK-01265 |
CCL24 Protein, Cynomolgus, Recombinant (His)
SCYA24,CK-beta-6,CK-β-6,Ckb |
Cynomolgus | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver. CCL24 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular w... | |||
TMPK-00704 |
CCL24 Protein, Human, Recombinant (hFc)
MPIF2,Ckb-6,SCYA24,CK-beta-6<... |
Human | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver. CCL24 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight... | |||
TMPJ-00801 |
UQCRH Protein, Human, Recombinant (GST)
Complex III subunit 6,Ubiquinol-c... |
Human | E. coli |
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) belongs to the UQCRH/QCR6 family, it is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase. This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. UQCRH may mediate formation of the complex between cytochromes c and c1. It may mediate formation of the complex between cytochromes c and c1. | |||
TMPH-01456 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc)
|
HHV-6B | E. coli |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc) is expressed in E. coli. | |||
TMPY-05498 |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
HDLQTL6,SR-BI,SRB1,CD36L... |
Human | HEK293 Cells |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5. | |||
TMPY-02891 |
PSG6 Protein, Human, Recombinant (His)
PSG12,PSG6,PSBG-6,pregnancy speci... |
Human | Baculovirus Insect Cells |
PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived fr... | |||
TMPH-01457 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)
|
HHV-6B | E. coli |
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs. Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P52539. | |||
TMPJ-00243 |
Serpin B6 Protein, Human, Recombinant (E. coli, His)
CAP,PI6,SERPINB6,Placental Throm<... |
Human | E. coli |
Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and se... | |||
TMPK-00712 |
ENPP3 Protein, Human, Recombinant (aa 48-157, His & Avi)
ENPP3,E-NPP 3,PDNP3,CD203c,PD-Ibeta,NPP3,NPPase,gp1... |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development and invasion of tumours. It was recently discovered that ENPP3 was upregulated during the window of implantation in the human endometrium but its functional relevance remains elusive. ENPP3 Protein, Human, Recombinant (aa 48-157, His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 17.21 ... | |||
TMPK-00573 |
ENPP3 Protein, Canine, Recombinant (His)
gp130RB13-6,PD-Iβ,NPP3,E-NPP 3,B1... |
Canine | HEK293 Cells |
Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development and invasion of tumours. It was recently discovered that ENPP3 was upregulated during the window of implantation in the human endometrium but its functional relevance remains elusive. ENPP3 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 96.19 kDa and the accessio... | |||
TMPK-00101 |
IL-6 Protein, Cynomolgus, Recombinant (His)
CDF,BSF-2,白介素,IL6,HGF,白细胞介素,Interleukin- |
Cynomolgus | HEK293 Cells |
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. | |||
TMPK-00711 |
ENPP3 Protein, Human, Recombinant (His & Avi)
gp130RB13-6,CD203c,NPPase,PDNP3,B... |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development and invasion of tumours. It was recently discovered that ENPP3 was upregulated during the window of implantation in the human endometrium but its functional relevance remains elusive. ENPP3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 99.97 kDa and the... | |||
TMPJ-00403 |
EphB1 Protein, Human, Recombinant (hFc)
EPHT2,EPH Tyrosine Kinase 2,EK6,Tyrosine-Protein Ki... |
Human | HEK293 Cells |
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule i... | |||
TMPH-01451 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Envelope glycoprotein B (His & Myc)
|
HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Envelope glycoprotein B (His & Myc) is expressed in E. coli. | |||
TMPK-00715 |
ENPP3 Protein, Human, Recombinant (aa 558-875, His)
PD-Ibeta,B10,E-NPP 3,PDNP3,NPP3,ENPP3,gp13... |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development and invasion of tumours. It was recently discovered that ENPP3 was upregulated during the window of implantation in the human endometrium but its functional relevance remains elusive. ENPP3 Protein, Human, Recombinant (aa 558-875, His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 39.06 kDa and t... | |||
TMPK-00713 |
ENPP3 Protein, Human, Recombinant (His & Avi), Biotinylated
NPP3,B10,PDNP3,NPPase,gp130RB13-6... |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development and invasion of tumours. It was recently discovered that ENPP3 was upregulated during the window of implantation in the human endometrium but its functional relevance remains elusive. ENPP3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 99.... | |||
TMPK-00714 |
ENPP3 Protein, Human, Recombinant (aa 48-157, His & Avi), Biotinylated
CD203c,PDNP3,NPPase,E-NPP 3,NPP3,PD-Iβ,gp130RB13- |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development and invasion of tumours. It was recently discovered that ENPP3 was upregulated during the window of implantation in the human endometrium but its functional relevance remains elusive. ENPP3 Protein, Human, Recombinant (aa 48-157, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular we... | |||
TMPY-04617 |
B7-H6 Protein, Cynomolgus, Recombinant (hFc)
natural killer cell cytotoxicity receptor 3 ligand 1,B |
Cynomolgus | HEK293 Cells |
B7-H6 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.2 kDa and the accession number is XP_005578557.1. | |||
TMPY-04495 |
B7-H6 Protein, Rat, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand 1,B |
Rat | HEK293 Cells |
B7-H6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.1 kDa and the accession number is XP_006223356.1. | |||
TMPY-00377 |
B7-H6 Protein, Human, Recombinant (hFc)
DKFZp686O24166,B |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.4 kDa and the accession number is Q68D85. | |||
TMPY-04618 |
B7-H6 Protein, Cynomolgus, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand 1,B |
Cynomolgus | HEK293 Cells |
B7-H6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the accession number is XP_005578557.1. | |||
TMPY-04619 |
B7-H6 Protein, Human, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand 1,DKFZp |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85. | |||
TMPY-02800 |
CGB7 Protein, Human, Recombinant (His)
chorionic gonadotropin beta subunit 7,chor... |
Human | Baculovirus Insect Cells |
CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CGB7 gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are... | |||
TMPY-00327 |
B7-H6 Protein, Rat, Recombinant (hFc)
B7H6,natural killer cell cytotoxicity rece... |
Rat | HEK293 Cells |
B7-H6 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.4 kDa and the accession number is XP_006223356.1. | |||
TMPJ-00463 |
BDH2 Protein, Human, Recombinant (His)
Oxidoreductase UCPA,Dehydrogenase/Reductase SDR Family Mem |
Human | E. coli |
3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate. | |||
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